"And he spake a parable unto them, saying, The ground of a certain rich man brought forth plentifully:
And he thought within himself, saying, What shall I do, because I have no room where to bestow my fruits?
And he said, This will I do: I will pull down my barns, and build greater; and there will I bestow all my fruits and my goods.
And I will say to my soul, Soul, thou hast much goods laid up for many years; take thine ease, eat, drink, and be merry.
But God said unto him, Thou fool, this night thy soul shall be required of thee: then whose shall those things be, which thou hast provided?
So is he that layeth up treasure for himself, and is not rich toward God."
Luke 12:16-21
The moral of this story is already laid out for us, and the lesson goes even further after this. The next verse is Christ instructing the disciples to "take no thought for your life," but to trust in the Lord and later to "seek ye the kingdom of God and all these things shall be added unto you" (verse 31), and even to sell what we have to give to others (verse 33). Clearly, the things of God come before the things of man.
So I guess the question is then, is God asking us all to become spiritual nomads, and to not build barns at all? Certainly, that is how he lived during his ministry, with God preparing the way before him. Missionaries taste a little bit of this idea, moving from place to place and teaching rather than settling down and building anything. However, God through his prophets also asks us to be prepared, and to "prepare every needful thing" in order to build, not barns, but temples, and people in the scriptures didn't all live as spiritual nomads... many of the missionaries did in the Book of Mormon, for a time, but they eventually went home to preach and to raise families as well.
I think the point here is not to tear down all the barns, but to recognize that our physical wealth is ephemeral. We should take care of our bodies and our families, but not obsess over building up physical wealth. We need to focus on being rich towards God, and if we run into the situation in the initial verse where we have an abundance that we can't store, then instead of building bigger barns, we should realize that we have enough, and God has given us the abundance in order to help others. Everything that we have, we should be willing to give up for God (including relationships/people and even our own lives where necessary as in Luke 14:26-26-33), but just as with Abraham and Isaac, we aren't always called to give it up, but rather to care for others and to use any material wealth we have to further God's work.
So, perhaps yes on being willing and ready to be a spiritual nomad for God when he asks us to go on a mission or move to a new area or to do something we might not be ready for... leaving our loved ones behind and going out into the unknown. But we should also be ready to do anything else for him, which means preparing and building sometimes, including maybe building a barn or other storage as Joseph did in Egypt to save everyone from the seven years of famine. The bottom line is to always be ready and willing to do as God asks, and to build treasure that we *can* take with us by becoming truly good people. God loves us... he wants us to be able to live, and love, and pursue the things that we love as well. We just have to remember that sometimes we go the wrong direction, and just as Amulek did in Alma 10, we need to pivot when the Lord asks us to pivot, and build what *he* asks us to build.